Faculty of Engineering and Natural Sciences · Molecular Biology and Genetics (English 30%) · Undergraduate
ECTS: 5 T+P+L: 3+0+0 Compulsory
Coordinator: Dr. Öğr. Üyesi Zeynep AYDIN SİNİRLİOĞLU
Course Objective
The aim of this course is for students to learn the concepts of genome, genome sequencing, genome expression, structural and functional genomes, proteome studies, and how to perform function and analysis of proteins.
Course Content
Genome definition, genome sequencing, genome anatomy, structural and functional analysis of the genome. The scope of proteomics includes: protein separation and identification methods, protein quantification methods, protein sequence analysis; protein structure and function.
Required Resources
T.A. Brown,Genomes 4, Taylor &Francis,Garland Science, (2023)
Twyman, R., Cfe, P.D., & George A., Garland Principles of Proteomics (2nd ed.).Science. (2013).
Explanations
A midterm, a final, and two short quizzes will be administered. • Attendance will be governed by the exam regulations set by the dean's office. • The final exam topics will cover all subjects but will primarily focus on topics covered after the midterm. • All exams will be in a traditional format and will include interpretive questions.
Rules
According to the regulations, a student who misses 30% of the total class hours (18 hours in total) will receive an absence (DZ) and fail the course. Attendance will be recorded with a signature.
Late Arrival: It's not just about arriving in class, but about joining the lesson on time. Remember that being late for three classes will count as one full absence. Late arrival is defined as: joining the class after the instructor has taken attendance and after the first 10 minutes have passed.
Seeking Help: Asking questions about the subject matter during class or in-person sessions is important for your education so you can learn the material in a timely manner. We encourage our students to seek help when needed.
Academic integrity: All work submitted for course grades is expected to be your own original work. Plagiarism or copying will result in disciplinary action and penalties in accordance with IZÜ's relevant regulations. You must provide medical reports if you are ill.
The assessments outlined in this program are fixed, and no additional compensatory assessments will be conducted to improve grades.
Course Learning Outcomes
- The student acquires basic knowledge about the genome and proteome.
- The student discusses the mechanisms involved in genome sequencing.
- Students gain fundamental knowledge about the structural and functional analysis of the genome.
- Students learn about protein separation, identification, and quantification.
- Students discuss protein sequence analysis, protein structure, and protein function.
Core Area Distribution
(44) Physical Sciences%60 (52) Engineering and Engineering Trades%40
Teaching Methods
ExpressionQuestion-AnswerDiscussion
Assessment & Evaluation
Performance Assignment ( Lab / Workshop / Field Work / Seminar / Presentation / Completion Study / ThesisTesting (Essay / Tests: True-Falls, multiple-choice, short answer, matching)
ECTS / Workload
| Activity | Quantity | Duration (h) | Total Workload |
|---|---|---|---|
| Course Duration (Including Exam Week) | 16 | 3 | 48 |
| Out of Class Study Period | 16 | 3 | 48 |
| Midterm | 1 | 2 | 2 |
| Quiz | 0 | 0 | 0 |
| Assignment | 2 | 13 | 26 |
| Practice | 0 | 0 | 0 |
| Final | 1 | 2 | 2 |
Course Schedule
| Week | Subject | Preparation |
|---|---|---|
| 1 | Introduction to genomics | Textbook |
| 2 | Gene and genome structure | Textbook |
| 3 | Genome mapping | Textbook |
| 4 | Genome sequencing technologies | Textbook |
| 5 | Genome annotation | Textbook |
| 6 | Functional and comparative genomics | Textbook |
| 7 | Transcriptomics | Textbook |
| 8 | Midterm exam | Midterm exam |
| 9 | Introduction to Proteomics | Textbook |
| 10 | Protein separation and characterization methods | Textbook |
| 11 | Methods for determining protein content | Textbook |
| 12 | Protein structure and sequence analysis methods | Textbook |
| 13 | Protein-protein / protein-DNA interaction methods | Textbook |
| 14 | Omics applications 1 | Textbook |
| 15 | Omics applications 2 | Textbook |
| 16 | Final | Final |


