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MBG 422 - Immunology

Faculty of Engineering and Natural Sciences · Molecular Biology and Genetics (English 30%) · Undergraduate

ECTS: 5 T+P+L: 3+0+0 Departmental Elective
Coordinator: Dr. Öğr. Üyesi Zeynep AYDIN SİNİRLİOĞLU
Instructors: Dr. Öğr. Üyesi Zeynep AYDIN SİNİRLİOĞLU

Course Objective

The aim of this course is to learn the tissues and organs of the immune system, the characteristics of natural and acquired immunity, the structure and functions of antigens and antibodies, and to explain the immunological mechanisms in detail.

Course Content

Natural and acquired immunity; Antibodies and their classification; Antigen identification and receptors; Antigen and antibody interactions; Immune response anatomy; Vaccinations; Immunodeficiency

Required Resources

Ivan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020

Explanations

There will be weekly quizzes, assignments, two midterm exams and a comprehensive final exam.
1. Quizzes will be in the last 20 minutes of the last lesson of the week and the content will be the topics of the previous week. No make-up will be given for quizzes in any way; However, your two lowest quiz scores will not be included in your overall evaluation.
2.Exam dates are as announced in the table. The subjects of the exams will be announced a reasonable time in advance. Make-up exams will be given for exams not taken within the framework of excuses accepted according to IZU regulations.
3.The final exam covers the topics covered throughout the semester. Final exam day, time and place will be announced by the Dean's Office.

Rules

Attendance: According to the regulations, if a student does not attend 30% of the total course hours, he/she will be absent from the course (DZ) and fail.
Arriving Late: You are expected to not only come to class but also attend class on time. Please note that arriving late to 3 classes will be counted as 1 complete absence. Arriving late to class is defined as follows: The instructor takes class attendance and attends class after the first 10 minutes of class.
Getting Help: It is important for your education that you learn the subject on time by asking your questions about the course during the lesson or during office hours. We recommend that our students get help when necessary.
Academic honesty: It is expected that the work that will be the subject of the course grade is entirely your own effort and work. In immoral cases such as plagiarism and copying, a disciplinary investigation will be initiated and you will be subject to the necessary penal sanctions in accordance with the relevant regulations of IZU.
The evaluations stated in this syllabus are fixed and no extra compensation will be made to increase the grade.

Course Learning Outcomes

  1. The student will have knowledge about the immune system and its types, which form the basis of immunology.
  2. The student will be informed about the organs and cells that make up the immune system.
  3. The student will have information about antigen, its types and antigen-recognizing receptors.
  4. The student will be informed about antibodies and their types and the immune response mechanisms that develop depending on them.
  5. The student will have knowledge about the molecules and pathways involved in the regulation of the immune response
  6. The student will be informed about vaccines and immunodeficiency

Core Area Distribution

(44) Physical Sciences%60 (72) Health%40

Teaching Methods

ExpressionQuestion-AnswerDiscussion

Assessment & Evaluation

HomeworkPerformance Assignment ( Lab / Workshop / Field Work / Seminar / Presentation / Completion Study / ThesisTesting (Essay / Tests: True-Falls, multiple-choice, short answer, matching)

ECTS / Workload

ActivityQuantityDuration (h)Total Workload
Course Duration (Including Exam Week)16348
Out of Class Study Period16348
Midterm122
Quiz000
Assignment21326
Practice000
Final122

Course Schedule

WeekSubjectPreparation
1immunology, principles and typesIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
2Natural and acquired immunity definitions and differencesIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
3Tissues that make up the immune systemIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
4Cells and their formations involved in the immune systemIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
5What is antigen, its types and the receptors that enable its recognitionIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
6Mechanisms and modes of action that form natural immunityIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
7Mechanisms and modes of action that form natural immunityIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
8Antibody and its typesIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
9Mechanisms and modes of action that create the adaptive immune responseIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
10Mechanisms and modes of action that create the adaptive immune responseIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
11VaccinationsIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
12Licensing and marketing of vaccinesIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
13ImmunodeficiencyIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
14Immunodeficiency treatmentsIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020
15The impact of immunology on our livesIvan Roitt, Jonathan Brostoff, David Male, David Roth, Victoria Male, Immunology, 9th edition, Elsevier, 2020