Faculty of Engineering and Natural Sciences · Molecular Biology and Genetics (English 30%) · Undergraduate
ECTS: 5 T+P+L: 3+0+0 Compulsory
Coordinator: Dr. Öğr. Üyesi Zeynep AYDIN SİNİRLİOĞLU
Instructors: Dr. Öğr. Üyesi Zeynep AYDIN SİNİRLİOĞLU
Course Objective
The aim of this course is for students to learn stem cell biology and its types, understand the molecular mechanisms of stem cells, understand the basis of tissue engineering, and learn the uses of stem cells in tissue engineering and the ethical problems that arise from them.
Course Content
Introduction to stem cell biology, types of stem cells, self-renewal and differentiation of stem cells, molecular mechanisms of stem cells, introduction to tissue engineering, biomaterials used in tissue engineering, tissue engineering applications, ethical problems related to tissue engineering and stem cell use.
Required Resources
Essentials of Stem Cell Biology, 2. Press, Editör:Robert Lanza and Anthony Atala, Elsevier Academic press
Tissue Engineering, 3. Press, Editör: Clemens Van Blitterswijk,Elsevier Academic press
Explanations
• A midterm, a final exam, and an assignment will be administered. • Students are required to present on the assigned topic for the assignment and submit a report on their research. • Absence exam regulations will be enforced in accordance with the rules set by the Dean's Office. • Final exams will cover all topics, but will primarily focus on topics related to the post-midterm exam. • All exams will be administered as standard exams and will include review questions.
Course Learning Outcomes
- The student acquires basic knowledge about stem cell biology.
- Students discuss the mechanisms related to the properties of stem cells.
- The student acquires basic knowledge about tissue engineering
- The student understands the importance of using stem cells in medicine.
- Students learn about tissue engineering applications
- Students discuss the ethical problems of tissue engineering and stem cell use.
Core Area Distribution
(42) Life Sciences%20 (52) Engineering and Engineering Trades%40 (72) Health%40
Teaching Methods
ExpressionQuestion-AnswerDiscussionSelf studyProject Based Learning (Including Field Work)
Assessment & Evaluation
HomeworkProject / DesignTesting (Essay / Tests: True-Falls, multiple-choice, short answer, matching)
ECTS / Workload
| Activity | Quantity | Duration (h) | Total Workload |
|---|---|---|---|
| Course Duration (Including Exam Week) | 16 | 3 | 48 |
| Out of Class Study Period | 16 | 3 | 48 |
| Midterm | 1 | 2 | 2 |
| Quiz | 0 | 0 | 0 |
| Assignment | 2 | 13 | 26 |
| Practice | 0 | 0 | 0 |
| Final | 1 | 2 | 2 |
Course Schedule
| Week | Subject | Preparation |
|---|---|---|
| 1 | Introduction to Stem Cell Biology | Slides |
| 2 | Embryonic development/ Embryonic and Adult stem cells | Slides |
| 3 | Stem cell pluripotency, self-renewal and differentiation | Slides |
| 4 | Inducible pluripotent stem cells | Slides |
| 5 | Cancer Stem Cells | Slides |
| 6 | The Molecular Mechanism of Stem Cells | Slides |
| 7 | Stem Cells and Regerenative medicine | Slides |
| 8 | Midterm | Midterm |
| 9 | Introduction to Tissue engineering | Slides |
| 10 | Biomaterials and scaffolds used in tissue engineering | Slides |
| 11 | The importance of cell interaction in tissue engineering | Slides |
| 12 | Applications of Tissue Engineering | Slides |
| 13 | The future of stem cell and tissue engineering and ethical issues | Slides |
| 14 | Student Presentations- I | Slides |
| 15 | Students presantations - II | Slides |
| 16 | Final Exam | Final Exam |


