Faculty of Engineering and Natural Sciences · Molecular Biology and Genetics (English 30%) · Undergraduate
Course Objective
1. To enable students to understand fundamental molecular genetic concepts.
2. To enable students to learn the structure of DNA and RNA.
3. To enable students to learn the concept of the central dogma and the 3D structures of proteins.
4. To enable students to understand different DNA types and their structural differences.
5. To explain in detail the stages from the codes in DNA to the protein synthesis process.
6. To enable students to interpret genetic diseases based on molecular genetic mechanisms.
Course Content
- Introduction To The Course
- Basics-Structure Of Nucleobases And Dna-Rna
- Different Forms Of Dna, End Of Dna Structure And Types Of Rnas
- Telomeric End Of Dna And Chromosomal Regulation Of Gene Functions
- Enzymes İnvolve İn Central Dogma
- Protein Structure
- Replication of DNA
- Gene Transcription And Rna Polymerase Function
- Protein Synthesis
- Transport Of Protiens And Mrna And Other Molecules
- Vesicular Transport
- Reviewing Of A Genetic Disorder
Explanations
Within the scope of this course, students will acquire the fundamental knowledge to maintain and understand the topics covered in the second semester's Molecular II course by the end of the semester. It is one of the most essential and comprehensive courses in the Molecular Biology and Genetics department. Students are provied with detailed reviews throughout the semester and they are introduced with other disciplines related to molecular genetics as general concept.
Rules
All students are required to attend 70% of the theoretical lectures and 80% of the laboratory lectures.
Students with a laboratory grade point average below 50 points will not be allowed to take the final exam.
The passing grade for the course is 50 points.
The allowed time for being late to class is the first 10 minutes.
The allowed time for being late to the exam is 20 minutes.
If anyone leaves the exam within the first 20 minutes, students who are late will not be admitted regardless of the 20-minute time limit.
Non-class activities (playing games, voice calls on the phone, texting on the phone, consuming strongly scented foods such as spices, garlic, and onions, personal hygiene, etc.) are prohibited during class.
Course Learning Outcomes
- Learn the structure and the functions of DNA and RNA
- Know the structure of the components of DNA and different forms of DNA (A, B, Z)
- Link between the DNA structure and the mutations
- Learn DNA replication, transcription and translation
- Have information about gene cloning
- Comprehend the recombinant DNA technology and the basics of genetic engineering
Core Area Distribution
Teaching Methods
Assessment & Evaluation
ECTS / Workload
| Activity | Quantity | Duration (h) | Total Workload |
|---|---|---|---|
| Course Duration (Including Exam Week) | 16 | 3 | 48 |
| Out of Class Study Period | 16 | 3 | 48 |
| Midterm | 1 | 2 | 2 |
| Quiz | 0 | 0 | 0 |
| Assignment | 0 | 0 | 0 |
| Practice | 0 | 0 | 0 |
| Final | 1 | 2 | 2 |
Course Schedule
| Week | Subject | Preparation |
|---|---|---|
| 1 | Introduction To The Course | Lesson materials will be shared |
| 2 | Basics-Structure Of Nucleobases And Dna-Rna | Lesson materials will be shared |
| 3 | Different Forms Of Dna, End Of Dna Structure And Types Of Rnas | Lesson materials will be shared |
| 4 | Telomeric End Of Dna And Chromosomal Regulation Of Gene Functions | Lesson materials will be shared |
| 5 | Enzymes İnvolve İn Central Dogma | Lesson materials will be shared |
| 6 | Central Dogma: Gene Transcription | Lesson materials will be shared |
| 7 | Protein 3D Structure | Exersices for the exam |
| 8 | Midterm | Exercises will be provided for the midterm exam |
| 9 | DNA Replication | Lesson materials will be shared |
| 10 | Protein Translation | Lesson materials will be shared |
| 11 | Molecular transport from the membranous structures | Lesson materials will be shared |
| 12 | Vesicular transport | Lesson materials will be shared |
| 13 | Association between molecular transport and central dogma | Lesson materials will be shared |
| 14 | Reviewing a genetic disease | Lesson materials will be shared |
| 15 | General review and exercises for the final exam | Lesson materials will be shared |
| 16 | Final Examination | Final Examination |


