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MBG 203 - Cell Biology I

Faculty of Engineering and Natural Sciences · Molecular Biology and Genetics (English 30%) · Undergraduate

ECTS: 7 T+P+L: 3+0+3 Compulsory
Coordinator: Dr. Öğr. Üyesi Mehmetali TİBATAN
Instructors: Dr. Öğr. Üyesi Mehmetali TİBATAN

Course Objective

The aims of the course can be summarized as follows:

  • To introduce the cell beyond its basic structure and explain its mechanisms of action,
  • How cells form tissues,
  • Detailed examination of the cell membrane structure and substance transport,
  • Intracellular molecular transport mechanisms,
  • Cytoskeleton structure and function,
  • Detailed functions and structures of organelles,
  • Cell culture studies in vitro,
  • Determination of cell growth rate.

Course Content

This course covers the properties of cells and cellular components, basic molecular cell biology, ATP production in the cell, cell growth rate determination, and cytotoxic test protocols.

Explanations

This course is the first part of the cell biology course, and advanced topics and laboratory applications are given in the second semester as Cell Biology-II. The content of the Cell Biology-I course consists of organelles, membrane structure and transport of substances across the membrane, membrane potential calculations, cell culture applications, cytoskeleton structure, intracellular substance transport, and tissue formation.

Rules

All students are required to attend 70% of the theoretical lectures and 80% of the laboratory lectures.
Students with a laboratory grade point average below 50 points will not be allowed to take the final exam.
The passing grade for the course is 50 points.
The allowed time for being late to class is the first 10 minutes.
The allowed time for being late to the exam is 20 minutes.
If anyone leaves the exam within the first 20 minutes, students who are late will not be admitted regardless of the 20-minute time limit.
Non-class activities (playing games, voice calls on the phone, texting on the phone, consuming strongly scented foods such as spices, garlic, and onions, personal care, etc.) are prohibited during class.

Course Learning Outcomes

  1. Will gain knowledge of cell components
  2. Will gain knowledge of structure and function of cellular membrane
  3. Will develop understanding the cellular mechanism of molecular transport
  4. Will understand the cytoskeleton function
  5. Will be able to organize cell culture and reviewing cellular morphology
  6. Will interpret the cellular shape changes under the microscope
  7. Will be able to test toxicological substance effects on the human cells
  8. Will acquire knowledge of importance of the membrane potential for the cellular energy metabolism and will be able to calculate the membrane potential of the cells
  9. Will explain the structure of mitochondrial membrane transport
  10. Will explain the ATP synthesis through the ETS and oxidative phosphorylation
  11. Will interpret the vesicular transport
  12. Will comprehend the cellular attachment and tissue formation association
  13. Will be able to interpret the cellular organization

Core Area Distribution

(42) Life Sciences%90 (72) Health%10

Teaching Methods

ExpressionQuestion-AnswerDiscussionExperiment - Test / Lab/ Workshop / Field Practice

Assessment & Evaluation

Performance Assignment ( Lab / Workshop / Field Work / Seminar / Presentation / Completion Study / ThesisTesting (Essay / Tests: True-Falls, multiple-choice, short answer, matching)

ECTS / Workload

ActivityQuantityDuration (h)Total Workload
Course Duration (Including Exam Week)16348
Out of Class Study Period16464
Midterm155
Quiz000
Assignment000
Practice14342
Final155

Course Schedule

WeekSubjectPreparation
1Introduction To The CourseCourse content will be shared
2Basics-definition of the cell and its compartmentsCourse content will be shared
3Chemical components of membraneCourse content will be shared
4Membranous organelles: Endoplasmic reticulumCourse content will be shared
505: Membraneous organelles: Golgi apparatusCourse content will be shared
6CytoskeletonCourse content will be shared
7MidtermMidterm
8Cellular digestionCourse content will be shared
9Energy Generation I: MitochondriaCourse content will be shared
10Transport Mechanisms Mediated by MembraneCourse content will be shared
11Transport Mechanisms Mediated by Vesicle and Neuronal PotentialCourse content will be shared
12Vesicular TransportCourse content will be shared
13Energy Generation: ChloroplastCourse content will be shared
14Tissue formation by cellular attachmentCourse content will be shared
15General reivew and preparation to the examCourse content will be shared
16Final ExamExam