Faculty of Engineering and Natural Sciences · Molecular Biology and Genetics (English 30%) · Undergraduate
ECTS: 7 T+P+L: 3+0+3 Compulsory
Coordinator: Dr. Öğr. Üyesi Mehmetali TİBATAN
Course Objective
Aim of this course;
- Introduction to Molecular Biology course aims to prepare students for the fundamental concepts and terminology of the molecular biology discipline.
- While doing so, it also aims to teach general methods in molecular biology, such as RNA-DNA isolation and PCR techniques, and to explain and familiarize students with their working principles and mechanisms.
- In addition to the basic concepts of molecular biology, teaching the detailed function and structure of the DNA is among the course objectives.
- The importance of central dogma in the fundemental functions of nucleic acids inthe cell will also be covered within this course.
- The course objectives also include teaching about experiments conducted in molecular biology, the types of model organisms used in these experiments, and the reasons for selecting these types.
Course Content
The course includes:
- General concepts; basic information such as DNA-RNA, nucleotide differences in nucleic acids,
- Use of micropipettes in molecular biology methods, nucleic acid isolation and PCR technique
- Types and structures of biomolecules (carbohydrates, fats, protein structure and the structure of nucleic acids),
- The concept of central dogma and its components,
- The basic structure of proteins and protein folding properties,
- The concept of model organisms used in experiments.
Required Resources
Campell Biology (12th edition) by Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Recommended Resources
Fundamental Molecular Biology, 3rd Edition Lizabeth A. Allison
Explanations
Midterm: 25%
Lab: 25%
Final:50%
Rules
- All students are required to attend 70% of the theoretical lectures and 80% of the laboratory lectures.
- Students with a laboratory grade point below 50 points will not be allowed to take the final exam.
- The passing grade for the course is 50 points.
- The allowed time for being late to class is the first 10 minutes.
- The allowed time for being late to the exam is 20 minutes.
- If anyone leaves the exam within the first 20 minutes, late students will not be admitted regardless of the 20-minute time tolerance.
- Non-class activities (playing games, making phone calls, phone texting, consuming strongly scented foods such as spices, garlic, and onions, personal care, etc.) are prohibited during class.
Course Learning Outcomes
- They will be able to understand the jargon used in the disciplines of molecular biology and genetics and acquire the necessary background.
- They will learn the pathway from DNA to protein and be will be able to explain the connection between them.
- Understand molecular mechanism inside the cell
- Learn to the regulation of gene expression
- Have knowledge about the latest developments and application areas in Molecular Biology and Genetics
- They will be able to learn about the 3D structure and folding features of proteins.
- Able to repeat the basic steps and application of the PCR technique in a laboratory setting.
- Able to use and calibrate a micropipette.
- They will learn concept of model organism and important experiments for the molecular biology in the science history
- Will gain knowledge about how enzymes work
- Will be able to explain detailed 3D structure and molecular structure of the DNA
Core Area Distribution
(42) Life Sciences%80 (72) Health%20
Teaching Methods
ExpressionQuestion-AnswerExercise and PracticeGuided PracticeExperiment - Test / Lab/ Workshop / Field Practice
Assessment & Evaluation
Performance Assignment ( Lab / Workshop / Field Work / Seminar / Presentation / Completion Study / ThesisTesting (Essay / Tests: True-Falls, multiple-choice, short answer, matching)
ECTS / Workload
| Activity | Quantity | Duration (h) | Total Workload |
|---|---|---|---|
| Course Duration (Including Exam Week) | 15 | 3 | 45 |
| Out of Class Study Period | 15 | 3 | 45 |
| Midterm | 1 | 2 | 2 |
| Quiz | 0 | 0 | 0 |
| Assignment | 0 | 0 | 0 |
| Practice | 13 | 3 | 39 |
| Final | 1 | 2 | 2 |
Course Schedule
| Week | Subject | Preparation |
|---|---|---|
| 1 | Introduction to the course | Course content will be shared |
| 2 | General concept | Course content will be shared |
| 3 | Biomolecules I; Lipids, Carbohydrates | Course content will be shared |
| 4 | Biomolecules II; Proteins-nucleic bases-energy molecules | Course content will be shared |
| 5 | Nucleic Acids | Course content will be shared |
| 6 | Proteins and folding properties | Course content will be shared |
| 7 | Midterm | Midterm |
| 8 | Enzymes-1 | Course content will be shared |
| 9 | Enzymes-II | Course content will be shared |
| 10 | Enzymes II continue- Enzyme inhibition types | Course content will be shared |
| 11 | Central dogma | Course material will be shared |
| 12 | Central dogma-continiuum | Course content will be shared |
| 13 | Model organism concept | Course content will be shared |
| 14 | Important experiments in molecular biology | Course content will be shared |
| 15 | General repeats and exam preparations | Course content will be shared |
| 16 | Final Exam | Final Exam |


